BDBM419863 US10464927, Compound I-11
SMILES CCN1CCN(Cc2ccc(Nc3ncc(F)c(n3)-c3ncnc4n(C5CCCC5)c(C)cc34)nc2)CC1
InChI Key InChIKey=IVURZNAEJYMDOR-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 419863
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: 300nMAssay Description:CDK6: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM D...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology
US Patent
Shanghai Xunhe Pharmaceutical Technology
US Patent
Affinity DataIC50: <20nMAssay Description:CDK4: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM DT...More data for this Ligand-Target Pair