BDBM419871 US10464927, Compound I-19

SMILES Fc1cnc(Nc2ccc(CN3CCN(CC3)C3CCCCC3)cn2)nc1-c1ccc2n(cc(C3CCC3)c2c1)C1CCCCC1

InChI Key InChIKey=BBPXSUYRPKRMFP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 419871   

TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology

US Patent
LigandPNGBDBM419871(US10464927, Compound I-19)
Affinity DataIC50: >500nMAssay Description:CDK6: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM D...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Shanghai Xunhe Pharmaceutical Technology

US Patent
LigandPNGBDBM419871(US10464927, Compound I-19)
Affinity DataIC50: <20nMAssay Description:CDK4: The test compound was dissolved in DMSO and diluted with a kinase buffer solution (20 mM HEPES-pH 7.5, 0.01% Triton X-100, 10 mM MgCl2, 2 mM DT...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent