BDBM419964 US10472364, Compound 49::US10570167, Cpd. # 49::US11034715, Cpd. # 49::US11208414, Cpd. # 49

SMILES COc1cccc(CC(OC[C@H]2O[C@H]([C@@H](F)[C@@H]2O)n2cnc3c(N)nc(Cl)nc23)(C(O)=O)C(O)=O)c1

InChI Key InChIKey=LLUUZTHMOMKPJI-DMVWFOPNSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 419964   

Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  839nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  2.38E+3nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  839nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  2.38E+3nMAssay Description:The ability of compounds to inhibit endogenous, cell-bound CD73 enzyme activity was demonstrated using SK-MEL-28 cells, which express CD73 on their s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  2.38E+3nMAssay Description:The ability of compounds to inhibit endogenous, cell-bound CD73 enzyme activity was demonstrated using SK-MEL-28 cells, which express CD73 on their s...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  839nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
Target5'-nucleotidase(Homo sapiens (Human))
Calithera Biosciences

US Patent
LigandPNGBDBM419964(US10472364, Compound 49 | US10570167, Cpd. # 49 | ...)
Affinity DataIC50:  839nMAssay Description:For measurements of soluble CD73 enzyme activity, recombinant CD73 was obtained from R&D Systems, Cat. No. 5795-EN-010. Serial dilutions of test comp...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent