BDBM420069 US10487086, Example I-57

SMILES COC(=O)Nc1ccc2-c3nc([nH]c3Cl)[C@H](CCCC(C)C(=O)Nc2c1)NC(=O)c1c(F)cc2ncn(C)c2c1F

InChI Key

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420069   

TargetCoagulation factor XI(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM420069(US10487086, Example I-57)
Affinity DataKi:  6.60nMAssay Description:The effectiveness of compounds of the present invention as inhibitors of the coagulation Factors XIa, VIIa, IXa, Xa, XIIa, plasma kallikrein or throm...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent