BDBM420187 (7S)-4-[(6-Chloropyrazolo[1,5-a]pyridin-5-yl)amino]-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-7-yl[(1R,4R)-2-oxa-5-azabicyclo[2.2.1]hept-5-yl]methanone::US10487092, Example 75

SMILES Clc1cn2nccc2cc1Nc1ncnc2sc3C[C@H](CCc3c12)C(=O)N1C[C@H]2C[C@@H]1CO2

InChI Key InChIKey=PBTMTOQZGPQPGI-NWANDNLSSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420187   

TargetIsoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) 344D](Homo sapiens (Human))
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US Patent
LigandPNGBDBM420187((7S)-4-[(6-Chloropyrazolo[1,5-a]pyridin-5-yl)amino...)
Affinity DataIC50:  56nMAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent