BDBM420205 US10485800, Cmpd ID FH::US10485800, Example 162

SMILES CN1CCN(Cc2ccc(cc2)-c2c[nH]c3ncc(cc23)-c2ccc(cc2)C(N)=O)CC1

InChI Key InChIKey=LEYAMEZHQDXXQV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 420205   

TargetMitogen-activated protein kinase kinase kinase 11(Homo sapiens (Human))
The University Of Rochester

US Patent
LigandPNGBDBM420205(US10485800, Cmpd ID FH | US10485800, Example 162)
Affinity DataIC50: <100nMAssay Description:200 ng (130 nM) MLK3 (Dundee, DU8313) was incubated with 1 μM inactive MKK7b (Dundee, DU703) in the presence of 2 μM cold ATP (Km) and 0.5 ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent