BDBM420962 US10479798, Compound 21

SMILES COc1cc2c3C[C@H](N)[C@H](Oc3ccc2cc1C#N)c1cc(F)c(F)cc1F

InChI Key InChIKey=OGGAKUIGELBYAA-GHTZIAJQSA-N

Data  2 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 420962   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
East China University Of Science And Technology

US Patent
LigandPNGBDBM420962(US10479798, Compound 21)
Affinity DataIC50:  2nMAssay Description:Screening Method:Name of method: Activity Evaluation of DPP4, Fluorescence.Instrument: Microplate reader, Envision (PerkinElmer, USA).Material: human...More data for this Ligand-Target Pair
Ligand InfoPDB
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
East China University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM420962(US10479798, Compound 21)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Ligand InfoPDB
In DepthDetails ArticlePubMed
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
East China University Of Science And Technology

US Patent
LigandPNGBDBM420962(US10479798, Compound 21)
Affinity DataKd:  0.177nMAssay Description:Binding affinity to DPP4 (unknown origin) expressed in baculovirus expressing systemMore data for this Ligand-Target Pair
Ligand InfoPDB