BDBM421182 7-(2-methyl-5-((2-methyl-2,4,6,7-tetrahydro-5H- pyrazolo[4,3-c]pyridin-5-yl)sulfonyl)phenyl)imidazo[2,1- f][1,2,4]triazin-4-amine::US10479795, Example 225

SMILES Cc1ccc(cc1-c1cnc2c(N)ncnn12)S(=O)(=O)N1CCc2nn(C)cc2C1

InChI Key InChIKey=ANUJNEIQXPBLDS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421182   

LigandPNGBDBM421182(7-(2-methyl-5-((2-methyl-2,4,6,7-tetrahydro-5H- py...)
Affinity DataIC50: >100nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421182(7-(2-methyl-5-((2-methyl-2,4,6,7-tetrahydro-5H- py...)
Affinity DataIC50: <100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent