BDBM421254 2-((3-(4-amino-2-(trifluoromethyl)imidazo[2,1- f][1,2,4]triazin-7-yl)-4-methylphenyl)sulfonyl)-2,5- diazabicyclo[2.2.1]heptan-7-ol::US10479795, Example 355

SMILES Cc1ccc(cc1-c1cnc2c(N)nc(nn12)C(F)(F)F)S(=O)(=O)N1CC2NCC1C2O

InChI Key InChIKey=FNASJMOYDYOGTL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 421254   

LigandPNGBDBM421254(2-((3-(4-amino-2-(trifluoromethyl)imidazo[2,1- f][...)
Affinity DataIC50: <500nMAssay Description:PI3Kδ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.). ...More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent
LigandPNGBDBM421254(2-((3-(4-amino-2-(trifluoromethyl)imidazo[2,1- f][...)
Affinity DataIC50: <100nMAssay Description:PI3K-γ:[γ-33P]ATP (10 mCi/mL) and Wheat Germ Agglutinin (WGA) YSi SPA Scintillation Beads was purchased from Perkin-Elmer (Waltham, Mass.)....More data for this Ligand-Target Pair
Ligand Info
In DepthDetails US Patent