BDBM42323 1-(10H-phenothiazin-2-yl)ethanone::MLS000047624::SMR000033635::cid_81131

SMILES CC(=O)c1ccc2Sc3ccccc3Nc2c1

InChI Key InChIKey=JWGBOHJGWOPYCL-UHFFFAOYSA-N

Data  8 KI  5 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 42323   

Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi:  300nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
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TargetAlpha-2A adrenergic receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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TargetMuscarinic acetylcholine receptor M1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

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TargetKappa-type opioid receptor [1-7](Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

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TargetD(3) dopamine receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

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TargetAlpha-2C adrenergic receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaGoogleScholar

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TargetAlpha-2B adrenergic receptor(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
GoogleScholar

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TargetMuscarinic acetylcholine receptor M2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataKi: >1.00E+4nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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TargetLysosomal acid glucosylceramidase(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataEC50: >5.00E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute, TSRI Assay ...More data for this Ligand-Target Pair

Target InfoPDBMMDBReactome pathwayKEGG
UniProtKB/SwissProt
B.MOADDrugBankantibodypediaGoogleScholar

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TargetCytochrome b-245 heavy chain(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataIC50:  5.00E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
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In DepthDetails PCBioAssay
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TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataIC50:  5.50E+3nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
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In DepthDetails PCBioAssay
Copy BDB DOI

TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataIC50:  129nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataIC50:  250nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails PCBioAssay
Copy BDB DOI

TargetNADPH oxidase 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay

LigandBDBM42323(1-(10H-phenothiazin-2-yl)ethanone | MLS000047624 |...)Copy SMILESCopy InChI

Affinity DataIC50:  156nMAssay Description:Data Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institut...More data for this Ligand-Target Pair

Target InfoReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPurchasePC cidPC sidPatentsSimilars

In DepthDetails PCBioAssay
Copy BDB DOI