BDBM424895 US10508120, Compound I-1399::US10577373, Compound I-1399::US11046698, Compound I-1399
SMILES CNc1cc(Nc2cccn([C@@H]3C[C@H]3F)c2=O)nc2c(cnn12)C(=O)NCC(C)(C)CO
InChI Key InChIKey=MPSKBHGTTIEAMV-UKRRQHHQSA-N
Data 3 Kd
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 424895
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi
US Patent
Nimbus Lakshimi
US Patent
Affinity DataKd: 5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair