BDBM4279 2-[(4-cyanophenyl)methylidene]propanedinitrile::Tyrphostin deriv. 10

SMILES N#C\[#6](=[#6]/c1ccc(cc1)C#N)C#N

InChI Key InChIKey=UUKLIKUNCGVVHN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4279   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4279(2-[(4-cyanophenyl)methylidene]propanedinitrile | T...)
Affinity DataIC50:  1.40E+6nMpH: 7.6 T: 2°CAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed