BDBM4290 (5-Methoxy-6-hydroxy-2-oxo-3-indolinidene)malononitrile::2-(6-hydroxy-5-methoxy-2-oxo-2,3-dihydro-1H-indol-3-ylidene)propanedinitrile::Tyrphostin deriv. 21

SMILES [#6]-[#8]-c1cc2\[#6](=[#6](/C#N)C#N)-[#6](=O)-[#7]-c2cc1-[#8]

InChI Key InChIKey=MAEZWIJGAMCORN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4290   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM4290((5-Methoxy-6-hydroxy-2-oxo-3-indolinidene)malononi...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of EGFR in human A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM4290((5-Methoxy-6-hydroxy-2-oxo-3-indolinidene)malononi...)
Affinity DataIC50:  6.00E+4nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed