BDBM4305 (2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phenylethyl]prop-2-enamide::Tyrphostin deriv. 50

SMILES C[C@H](NC(=O)C(=C\c1ccc(O)c(O)c1)\C#N)c1ccccc1

InChI Key InChIKey=UMGQVUWXNOJOSJ-DGGAMASNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4305   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4305((2E)-2-cyano-3-(3,4-dihydroxyphenyl)-N-[(1S)-1-phe...)
Affinity DataIC50:  860nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed