BDBM430624 Beta-D-N4-hydroxycytidine::EIDD-1931::N(4)-Hydroxycytidine::N4-Hydroxycytidine::NHC::Uridine, 4-oxime
SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc(NO)nc1=O
InChI Key InChIKey=XCUAIINAJCDIPM-XVFCMESISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 430624
Affinity DataIC50: 150nMAssay Description:At 48 hours prior to infection, Calu-3 2B4 cells were plated in a 96-well black-walled clear bottom plate at 5x104 cells/well. A 10 mM stock of NHC w...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Vero E6 cells were plated at 20,000 cells/well in a 96-well plate. 24hr later, medium containing a dose response of NHC was added concurrent with SAR...More data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Calu-3 2B4 cells were adsorbed with MOI 0.1 PFU/cell of SARS-CoV-2 (2019-nCoV/USA-WA1/2020 strain) at 37°C. Plates were manually rocked every 10 min ...More data for this Ligand-Target Pair
Affinity DataIC50: 80nMAssay Description:Calu-3 2B4 cells were adsorbed with MOI 0.1 PFU/cell of SARS-CoV-2 (2019-nCoV/USA-WA1/2020 strain) at 37°C. Plates were manually rocked every 10 min ...More data for this Ligand-Target Pair