BDBM430706 US10544150, Compound 72::[1,1'-biphenyl]-4-yl(8-methyl-3-(4-methyl-2-phenylthiazol-5-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone

SMILES CC1N(CCn2c1nnc2-c1sc(nc1C)-c1ccccc1)C(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=PWQDHXJNNSSJGY-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430706   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM430706(US10544150, Compound 72 | [1,1'-biphenyl]-4-yl(8-m...)
Affinity DataKi: <500nMAssay Description:The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent