BDBM430751 (3-(2-(2,4-difluorophenyl)thiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)(4-(thiophen-2-yl)phenyl)methanone::US10544150, Compound 170

SMILES Fc1ccc(-c2nc(cs2)-c2nnc3CN(CCn23)C(=O)c2ccc(cc2)-c2cccs2)c(F)c1

InChI Key InChIKey=VYNXIHKOSFTZTQ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430751   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM430751((3-(2-(2,4-difluorophenyl)thiazol-4-yl)-5,6-dihydr...)
Affinity DataKi: <500nMAssay Description:The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent