BDBM430773 (4-(thiophen-2-yl)phenyl)(3-(2-(thiophen-2-yl)thiazol-4-yl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)methanone::US10544150, Compound 194

SMILES O=C(N1CCn2c(C1)nnc2-c1csc(n1)-c1cccs1)c1ccc(cc1)-c1cccs1

InChI Key InChIKey=JIAHPKUVJGANOT-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430773   

TargetNeuromedin-K receptor(Homo sapiens (Human))
Ogeda

US Patent
LigandPNGBDBM430773((4-(thiophen-2-yl)phenyl)(3-(2-(thiophen-2-yl)thia...)
Affinity DataKi: <500nMAssay Description:The ability of the compounds of the invention to inhibit the binding of the NK-3 receptor selective antagonist SB222200 was assessed by an in vitro r...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent