BDBM430888 US10550102, Example 45b

SMILES CCOC(=O)c1cnn(c1C)-c1cccc(n1)-c1cccc2CCC(Nc3ccc(cc3C)C3CCN(CC3)C(=O)OC(C)(C)C)c12

InChI Key InChIKey=GICHLMDIOIFJEH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430888   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430888(US10550102, Example 45b)
Affinity DataEC50:  3.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent