BDBM430902 US10550102, Example (+) or (-)-46-4

SMILES Cc1c(cnn1-c1cccc(n1)-c1cccc2CCC(Nc3ccc(C4CCN(CC4)C(=O)CC4CC4)c(F)c3C)c12)C(O)=O

InChI Key InChIKey=DHGAHHNCUJISSK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430902   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430902(US10550102, Example (+) or (-)-46-4)
Affinity DataEC50:  1.40nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent