BDBM430939 US10550102, Example 31-3

SMILES CCc1c(cnn1-c1cccc(n1)-c1cccc2CC[C@H](Oc3ccc(C4CCN(CC4)C(=O)[C@@H](C)CO)c(CC)c3)c12)C(O)=O

InChI Key InChIKey=GJSBYIBLLKPDLR-WYOOIXGGSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 430939   

TargetGuanylate cyclase soluble subunit alpha-1/beta-1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM430939(US10550102, Example 31-3)
Affinity DataEC50:  0.5nMAssay Description:Chinese hamster ovary (CHO) cells overexpressing soluble guanylate cyclase were generated to test the effect of sGC activators in a cellular context....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent