BDBM431868 US10550114, Compound 1b

SMILES CCC(=O)Nc1ccc2[nH]c(=O)n(C3CCN(Cc4ccc(cc4)-c4nc5cc[nH]c(=O)c5cc4-c4ccccc4)CC3)c2c1

InChI Key InChIKey=NFXSQFADJLOQHR-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 431868   

TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431868(US10550114, Compound 1b)
Affinity DataKd:  62nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Technische UniversitÄT Dortmund

US Patent
LigandPNGBDBM431868(US10550114, Compound 1b)
Affinity DataIC50:  7.5nMAssay Description:iFLiK and HTRF studies were carried out as described in Z. Fang, J. R. Simard, D. Plenker, H. D. Nguyen, T. Phan, P. Wolle, S. Baumeister, D. Rauh, A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB