BDBM431871 1-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azabicyclo[3.1.0]hexan-4-yl)ethynyl)phenyl)-1H- pyrazolo[3,4-b]pyridine-3-carboxamide::US10550117, Compound 1

SMILES CN1[C@@H]2C[C@@H]2[C@@](O)(C#Cc2cccc(c2)-n2nc(C(N)=O)c3cccnc23)C1=O

InChI Key InChIKey=GMAWUPHGBKLOEK-MRUHUIDDSA-N

Data  1 KI

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 431871   

LigandPNGBDBM431871(1-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azab...)
Affinity DataKi:  0.880nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB