BDBM431888 1-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azabicyclo[3.1.0]hexan-4-yl)ethynyl)phenyl)-7- methoxyimidazo[1,5-a]pyridine-3-carboxamide::US10550117, Compound 4

SMILES COc1ccn2c(nc(-c3cccc(c3)C#C[C@]3(O)[C@H]4C[C@H]4N(C)C3=O)c2c1)C(N)=O

InChI Key InChIKey=NFYGFCMIZMKUNI-MFEFFIJZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 431888   

TargetMitogen-activated protein kinase kinase kinase 14(Homo sapiens (Human))
Genentech

US Patent
LigandPNGBDBM431888(1-(3-(((1R,4R,5S)-4-hydroxy-2-methyl-3-oxo-2- azab...)
Affinity DataKi:  0.0500nMAssay Description:The ability of the nuclear factor-kappa B (NF-kB)-inducing kinase (NIK) to catalyze the hydrolysis of adenosine-5′-triphosphate (ATP) was monit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent