BDBM431946 US10576064, Example I-19
SMILES Fc1c(Cl)cccc1[C@H]1[C@H]2[C@H](CCNC2=O)N(CC2CCC2)[C@@]11C(=O)Nc2cc(Cl)ccc12
InChI Key InChIKey=FZWRMSNIZHOASX-UGCAPWQASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 431946
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 240nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair