BDBM432014 US10576064, Example I-235
SMILES OC(=O)c1ccc(cc1)N1C[C@@H]2[C@@H]([C@@H](c3cccc(Cl)c3F)[C@]3(N2CC2CCCCC2)C(=O)Nc2cc(Cl)ccc32)C1=O
InChI Key InChIKey=UOKCCCWRVOUWDJ-CPWWYQHDSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 432014
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 980nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair