BDBM432034 US10576064, Example I-268
SMILES NC(=O)c1ccc(cc1)N1CC[C@H]2[C@H]([C@H](c3cccc(Cl)c3F)[C@@]3(N2CC2CC2)C(=O)Nc2cc(Cl)ccc32)C1=O
InChI Key InChIKey=HIEAMRFJIWRBLX-GURVGDRESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 432034
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 26nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair