BDBM432042 US10576064, Example I-283
SMILES CCOc1cccc(CN2[C@H]3CN(C(=O)[C@H]3[C@H](c3cccc(Cl)c3F)[C@]22C(=O)Nc3cc(Cl)ccc23)c2ccc(cc2)C(=O)NO)c1
InChI Key InChIKey=TXEOBRAQWREDST-VLWKUZPGSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 432042
TargetE3 ubiquitin-protein ligase Mdm2 [23-127](Homo sapiens (Human))
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 4nMAssay Description:This assay is used to determine whether the compounds inhibit the p53-MDM2 interaction and thus restore p53 function.15 μL of compound in 20% DM...More data for this Ligand-Target Pair