BDBM432269 N-[6-(4-Methoxyphenyl)pyrazin-2-yl]-N-(1-methylpiperidin-4-yl)thiophene-2-::US10577360, Example 132
SMILES COc1ccc(cc1)-c1cccc(n1)N(C1CCN(C)CC1)C(=O)c1cccs1
InChI Key InChIKey=JMFRWIXBZRDEAX-UHFFFAOYSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 432269
Affinity DataKi: <100nMAssay Description:To investigate binding properties of test compounds to human μ-opioid receptor, transfected CHO-K1 cell membranes and [3H]-DAMGO (Perkin Elmer, ...More data for this Ligand-Target Pair
TargetVoltage-dependent calcium channel subunit alpha-2/delta-1(Homo sapiens (Human))
Esteve Pharmaceuticals
US Patent
Esteve Pharmaceuticals
US Patent
Affinity DataKi: >5.00E+3nMAssay Description:Human α2δ-1 enriched membranes (2.5 μg) were incubated with 15 nM of radiolabeled [3H]-Gabapentin in assay buffer containing Hepes-KOH...More data for this Ligand-Target Pair