BDBM432836 N-((1R,3R,5S)-8-(((1r,4R)-4- aminocyclohexyl)sulfonyl)-8- azabicyclo[3.2.1]octan-3-yl)-5- cyclopropylisoxazole-3-carboxamide::US10577363, Compound 539

SMILES N[C@H]1CC[C@@H](CC1)S(=O)(=O)N1[C@H]2CC[C@@H]1C[C@@H](C2)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=JYZQPJRVTADXNE-BSBCAUIJSA-N

Data  1 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 432836   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM432836(N-((1R,3R,5S)-8-(((1r,4R)-4- aminocyclohexyl)sulfo...)
Affinity DataIC50:  1.30nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB