BDBM433080 N-((2S,4S)-1-((((1R,3R)-3- aminocyclopentyl)methyl)sulfonyl)-2- methylpiperidin-4-yl)-5- cyclopropylisoxazole-3-carboxamide::US10577363, Compound 784

SMILES C[C@H]1C[C@H](CCN1S(=O)(=O)C[C@@H]1CC[C@@H](N)C1)NC(=O)c1cc(on1)C1CC1

InChI Key InChIKey=BHNXIQIJVONHDU-XNISGKROSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433080   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM433080(N-((2S,4S)-1-((((1R,3R)-3- aminocyclopentyl)methyl...)
Affinity DataIC50:  1.29nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent