BDBM433085 N-((1R,3R,5S)-8-(((1r,4R)-4- aminocyclohexyl)sulfonyl)-8- azabicyclo[3.2.1]octan-3-yl)-5- ethylisoxazole-3-carboxamide::US10577363, Compound 789

SMILES CCc1cc(no1)C(=O)N[C@@H]1C[C@@H]2CC[C@H](C1)N2S(=O)(=O)[C@H]1CC[C@H](N)CC1

InChI Key InChIKey=BRDUOZOYXBJEAH-DCHCCWQYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433085   

TargetHistone-lysine N-methyltransferase SMYD3(Homo sapiens (Human))
Epizyme

US Patent
LigandPNGBDBM433085(N-((1R,3R,5S)-8-(((1r,4R)-4- aminocyclohexyl)sulfo...)
Affinity DataIC50:  1.59nMAssay Description:The assays were all performed in a buffer consisting of 25 mM Tris-Cl pH 8.0, 1 mM TCEP, 0.005% BSG, and 0.005% Tween 20, prepared on the day of use....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent