BDBM433340 US10561657, Example 17

SMILES O=C(C1CC(C1)Nc1nn(cc1-c1ncnc2[nH]ccc12)C(CC#N)C1CCCC1)N1CCOCC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 433340   

TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Centaurus Biophrama

US Patent
LigandPNGBDBM433340(US10561657, Example 17)
Affinity DataIC50: <20nMAssay Description:A testing platform for kinase activity of JAK2 (wild type and V617F mutant type) was established based on Homogeneous Time-Resolved Fluorescence (HTR...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent