BDBM434619 US10562902, Compound 25

SMILES CO[C@@H]1CC[C@@H](CC1)Nc1nc(Nc2cc(C)ns2)nc2ccn(-c3cnn(C)c3)c12

InChI Key InChIKey=RIYQJWSHAKXWOO-FZNQNYSPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434619   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434619(US10562902, Compound 25)
Affinity DataIC50:  550nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent