BDBM434642 US10562902, Compound 48

SMILES CNC(=O)c1csc(Nc2nc(N(C)C3CCOCC3)c3n(ccc3n2)-c2cnn(C)c2)c1

InChI Key InChIKey=UPMRNKNMLUOXEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 434642   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Beijing Hanmi Pharmaceutical

US Patent
LigandPNGBDBM434642(US10562902, Compound 48)
Affinity DataIC50: <100nMAssay Description:IRAK4 kinase (purchased from Life Technologies, Cat. No.: PR5612U) was diluted to 2 folds of the final concentration (the final concentration is 0.76...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent