BDBM435028 (2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-3- hydroxy-N-[[3-isopropyl-2,4-dioxo-1-[4- (trifluoromethyl)phenyl]pyrimidin-5- yl]methyl]pyrrolidine-2-carboxamide::US10584116, Example 8

SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2[C@@H](O)CCN2S(=O)(=O)c2cc3cc(F)ccc3o2)cn(-c2ccc(cc2)C(F)(F)F)c1=O

InChI Key InChIKey=IYMRWKNCZYWXPC-URXFXBBRSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435028   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM435028((2S,3S)-1-(5-fluorobenzofuran-2-yl)sulfonyl-3- hyd...)
Affinity DataIC50:  64nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent