BDBM435053 (2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3- isopropyl-2,4-dioxo-1-[5-(trifluoromethyl)-2- pyridyl]pyrimidin-5-yl]methyl]pyrrolidine-2- carboxamide::US10584116, Example 33

SMILES CC(C)n1c(=O)c(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3ccccc3o2)cn(-c2ccc(cn2)C(F)(F)F)c1=O

InChI Key InChIKey=OOVNFOVAFVAUEB-FQEVSTJZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435053   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM435053((2S)-1-(benzofuran-2-ylsulfonyl)-N-[[3- isopropyl-...)
Affinity DataIC50:  44nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent