BDBM435064 (2S)-1-(4-fluorobenzofuran-2-yl)sulfonyl-N- [[1-isopropyl-2-oxo-5-[4- (trifluoromethyl)phenyl]-3- pyridyl]methyl]pyrrolidine-2-carboxamide::US10584116, Example 44

SMILES CC(C)n1cc(cc(CNC(=O)[C@@H]2CCCN2S(=O)(=O)c2cc3c(F)cccc3o2)c1=O)-c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=BRNFYDHNQCOLDA-DEOSSOPVSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435064   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Ea Pharma

US Patent
LigandPNGBDBM435064((2S)-1-(4-fluorobenzofuran-2-yl)sulfonyl-N- [[1-is...)
Affinity DataIC50:  440nMAssay Description:Human TRPA1 Expression PlasmidUsing cDNA encoding human TRPA1 (GenBank accession No. NM_007332) (manufactured by Kazusa DNA Research Institute, item ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent