BDBM435230 US10568874, Example Table 1.3::US10919852, Compound TABLE 1.328::US11135210, TABLE 1.3::US11708326, Compound TABLE 1.328

SMILES CCOc1cc(NC2CCc3c2cccc3-c2cccc(OCCCN3CCC(C)(F)CC3)c2C)c(Cl)cc1CNC[C@@H]1CCC(=O)N1

InChI Key InChIKey=PENMIXPBBWGTGL-GZMKETDRSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 435230   

TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM435230(US10568874, Example Table 1.3 | US10919852, Compou...)
Affinity DataIC50:  253nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W/V...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM435230(US10568874, Example Table 1.3 | US10919852, Compou...)
Affinity DataIC50:  253nMAssay Description:96 Well plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1(Homo sapiens (Human))
Chemocentryx

US Patent
LigandPNGBDBM435230(US10568874, Example Table 1.3 | US10919852, Compou...)
Affinity DataIC50:  253nMAssay Description:Plates were coated with 1 μg/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W/V...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death protein 1(Homo sapiens)
Chemocentryx

US Patent
LigandPNGBDBM435230(US10568874, Example Table 1.3 | US10919852, Compou...)
Affinity DataIC50:  253nMAssay Description:96 Well plates were coated with 1 g/mL of human PD-L1 (obtained from R&D) in PBS overnight at 4° C. The wells were then blocked with 2% BSA in PBS (W...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent