BDBM435241 8-(((trans)-2-(3-methyl-1,2,4- oxadiazol-5-yl) cyclopropanecarboxamido)methyl)-N- (pyridin-3-yl)-5-(3-(trifluoromethyl) phenyl)-3,4-dihydroisoquinoline- 2(1H)-carboxamide (mixture of 2 isomers)::US10568876, Example 6

SMILES Cc1noc(n1)[C@H]1C[C@@H]1C(=O)NCc1ccc(-c2cccc(c2)-n2ccnn2)c2CCN(Cc12)C(=O)Nc1cccnc1

InChI Key InChIKey=BYIWITMQICNHAU-SVBPBHIXSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435241   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435241(8-(((trans)-2-(3-methyl-1,2,4- oxadiazol-5-yl) cyc...)
Affinity DataIC50:  100nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent