BDBM435246 N-(tert-butyl)-5-(3-methoxyphenyl)-8- (((trans)-2-(3-methyl-1,2,4-oxadiazol-5- yl)cyclopropanecarboxamido)methyl)- 3,4-dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 11

SMILES COc1cccc(c1)-c1ccc(CNC(=O)[C@@H]2C[C@H]2c2nc(C)no2)c2CN(CCc12)C(=O)NC(C)(C)C

InChI Key InChIKey=UXTWCRDHZBXXGV-DNQXCXABSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435246   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435246(N-(tert-butyl)-5-(3-methoxyphenyl)-8- (((trans)-2-...)
Affinity DataIC50:  3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent