BDBM435250 5-(3-methoxyphenyl)-8-(((trans)-2- phenylcyclopropanecarboxamido) methyl)-N-(pyridin-2-yl)-3,4- dihydroisoquinoline-2(1H)- carboxamide (mixture of 2 isomers)::US10568876, Example 15

SMILES COc1cccc(c1)-c1ccc(CNC(=O)[C@@H]2C[C@H]2c2ccccc2)c2CN(CCc12)C(=O)Nc1ccccn1

InChI Key InChIKey=MGKPRYRMFWBOBE-URLMMPGGSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435250   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435250(5-(3-methoxyphenyl)-8-(((trans)-2- phenylcycloprop...)
Affinity DataIC50:  3.11E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent