BDBM435355 (trans)-N-((2-(2-hydroxy-2- methylpropanoyl)-5-(3- (trifluoromethyl)phenyl)-1,2,3,4- tetrahydroisoquinolin-8-yl)methyl)-2-(3- methyl-1,2,4-oxadiazol-5- yl)cyclopropanecarboxamide (mixture of 2 isomers)::US10568876, Example 116

SMILES Cc1noc(n1)[C@H]1C[C@@H]1C(=O)NCc1ccc(-c2cccc(c2)C(F)(F)F)c2CCN(Cc12)C(=O)C(C)(C)O

InChI Key InChIKey=JSPBEIZSGUUVPW-VXKWHMMOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435355   

TargetDiacylglycerol O-acyltransferase 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM435355((trans)-N-((2-(2-hydroxy-2- methylpropanoyl)-5-(3-...)
Affinity DataIC50:  1.58E+3nMAssay Description:DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent