BDBM4354 (2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)but-2-enoic acid::benzylidenemalononitrile (BMN) deriv. 38

SMILES COc1cc(ccc1O)C(\C)=C(/C#N)C(O)=O

InChI Key InChIKey=NFHQLTFHKJHSIE-VQHVLOKHSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4354   

TargetEpidermal growth factor receptor(Homo sapiens (Human))
Hebrew University Of Jerusalem

LigandPNGBDBM4354((2E)-2-cyano-3-(4-hydroxy-3-methoxyphenyl)but-2-en...)
Affinity DataKi:  3.41E+5nM IC50:  1.10E+6nMAssay Description:The activity of EGFR, preactivated with EGF, is measured by its ability to transfer terminal phosphate from [gamma-32P]ATP to poly(GAT) substrate.More data for this Ligand-Target Pair
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