BDBM435404 US10570116, Compound C12

SMILES Cn1cc(cn1)C(=O)C1CCN(CC1)C(=O)CC1(Cc2nc3ccccc3c(=O)[nH]2)CC1

InChI Key InChIKey=OIHAQLWXPNRBJG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 435404   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435404(US10570116, Compound C12)
Affinity DataIC50:  7.10E+3nMAssay Description:PARP-1: The autoparsylation assay is performed as 384-well HTRF® (Cisbio, Codolet, France) assay format in Greiner low volume nb 384-well microtiter ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435404(US10570116, Compound C12)
Affinity DataIC50:  1nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM435404(US10570116, Compound C12)
Affinity DataIC50:  2.20nMAssay Description:TNKS 1 and 2: The activity ELISA is performed in 384 well Glutathione coated microtiter plates (Express capture Glutathione coated plate, Biocat, Hei...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent