BDBM435483 US10570118, Example 37

SMILES Nc1nccc(c1F)-c1cccc(c1CO)-n1c(cc2cc(ccc2c1=O)C1CC1)C1CCN(C1)C(=O)C=C

InChI Key InChIKey=SOVJMYPPPVFVQI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 435483   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM435483(US10570118, Example 37)
Affinity DataIC50:  620nMAssay Description:A Lanthscreen Eu Kinase Binding assay (Life Technologies) was performed to quantitate the ability of test compounds to bind to BTK. The assay is base...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent