BDBM435711 US10570155, Compound 1II::US11332479, Compound 1II
SMILES CN1CCN(CCNc2nccc(n2)-c2c(nc3occn23)-c2cccc(O)c2)S1(=O)=O
InChI Key InChIKey=XPYMPMCHKMTXSB-UHFFFAOYSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 435711
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 3.23nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 1.85nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [696-1022,L858R](Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 2.95nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 3.23nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase B-raf [V600E](Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 1.85nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
Korea Institute Of Science And Technology
US Patent
Korea Institute Of Science And Technology
US Patent
Affinity DataIC50: 2.95nMAssay Description:Reaction biology kinase hotspot service (http://www.reactionbiology.com) was used to measure IC50. In a final reaction volume of 25 μL, kinase (...More data for this Ligand-Target Pair