BDBM435904 2-(2,6-dichlorophenyl)-1-((1S,3R)-3-(hydroxymethyl)-1-methyl-5-(1H-pyrazol-4-yl)-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one::US10611751, Example 8
SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2-c1cn[nH]c1)C(=O)Cc1c(Cl)cccc1Cl
InChI Key
Data 3 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 435904
Affinity DataEC50: 13.4nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
Affinity DataEC50: 6.40nMAssay Description:Positive allosteric modulation of human D1 receptor in HEK293 cells assessed as increase in cyclic AMP production measured after 60 mins in presence ...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Positive allosteric modulation of human D1 receptor expressed in HEK293 assessed as cAMP production incubated for 60 mins by HTRF assayMore data for this Ligand-Target Pair