BDBM436045 2-(2-fluorophenyl)-1-((1S,3R)- 3-(hydroxymethyl)-1-methyl- 5-(1H-pyrazol-4-yl)-3,4- dihydroisoquinolin-2(1H)- yl)ethan-1-one::US10611751, Example 13

SMILES C[C@@H]1N([C@@H](CO)Cc2c1cccc2-c1cn[nH]c1)C(=O)Cc1ccccc1F

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436045   

TargetD(1A) dopamine receptor(Homo sapiens (Human))
Eli Lilly

US Patent
LigandPNGBDBM436045(2-(2-fluorophenyl)-1-((1S,3R)- 3-(hydroxymethyl)-1...)
Affinity DataEC50:  484nMAssay Description:The PAM activity of the compounds of the present invention may be measured essentially as described in Svensson et al., An Allosteric Potentiator of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent