BDBM436178 US10577373, Compound I-1387

SMILES CNc1cc(nc2c(cnn12)C(=O)N[C@H]1CC[C@H]1O)C1=CN(C(C)C)C2N=CC(F)=CC12

InChI Key InChIKey=PHBQRCXMYRAMRT-VIPPDZDWSA-N

Data  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 436178   

TargetNon-receptor tyrosine-protein kinase TYK2 [556-888](Homo sapiens (Human))
Nimbus Lakshimi

US Patent
LigandPNGBDBM436178(US10577373, Compound I-1387)
Affinity DataKd:  5.5nMAssay Description:Binding constants for compounds of the present invention against the JH2 domain were determined by the following protocol for a KINOMEscan® assay (Di...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent